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Greater Manchester mayor’s victory in Makerfield clears way for a bid to unseat Starmer as prime minister.

Greater Manchester Mayor Andy Burnham has cruised to victory in a high-stakes by-election in northern England, paving the way for him to challenge Prime Minister Keir Starmer for the leadership of the Labour Party and the United Kingdom.

Burnham defeated his closest challenger Robert Kenyon, the candidate for the anti-immigration Reform UK, in the seat of Makerfield, vote results showed early on Friday, securing the House of Commons seat he needs to mount a bid for the prime ministership.

“Everyone knows that politics is not working,” Burnham said in his victory speech.

“Everyone can feel that the country isn’t where it should be. Tonight could just be the turning point. From here on, I will give everything I have got to make it so.”

Burnham’s victory is likely to either precipitate Starmer’s resignation or set off a leadership contest pitting the prime minister against the outgoing mayor and Wes Streeting, the former health secretary.

Burnham is widely considered a strong favourite to become the next prime minister if he challenges Starmer.

In an Ipsos poll published earlier this week, Burnham was chosen by 25 percent of British adults as the preferred prime minister, compared to 12 percent for Starmer.

If he does succeed Starmer, Burnham, who was the early favourite in the 2015 Labour leadership race before coming second to Jeremy Corbyn, would be the UK’s seventh prime minister since the country voted for Brexit in 2016.

After leading Labour to a thumping election victory in 2024, Starmer has been under mounting pressure to step down amid widespread public dissatisfaction with his leadership.

Calls for his resignation within Labour have mounted since the party suffered crushing losses in local and regional elections in May.

Twenty ministers have resigned from Starmer’s government in less than two years, nearly half of whom expressed a loss of confidence in his leadership or clashed with him on policy, including Streeting.

Starmer has rebuffed calls to resign, pledging to fight any challenge to his leadership and insisting that such a contest would be a “bad thing for the country”.

Burnham – dubbed the “king of the north” for his grassroots appeal across northern England and his willingness to challenge Westminster – ran on the promise to “change Labour” to “change politics and change the country”.

As mayor of Greater Manchester, Burnham built an avid following across the UK’s less developed northern regions by channelling populist themes about elite apathy and industrial decline.

First elected mayor in 2017, and re-elected in 2021 and 2024, he has criticised the UK’s political system as “too London-centric” and taken aim at neoliberal economic policies and trickle-down economics that did not “trickle down very much at all”.

Burnham, who served in several ministerial portfolios under Prime Ministers Tony Blair and Gordon Brown, had been the narrow favourite in the race, holding a five-point lead over Kenyon in an opinion poll released on Saturday by pollster Opinium.

Labour’s Josh Simons, who previously held the seat of Makerfield, triggered the by-election last month by resigning his seat to allow Burnham to challenge Starmer.

About 75,000 people were eligible to vote in the district, located about 320km (200 miles) northwest of London.

Turnout was 58.75 percent, up from 52.4 percent at the 2024 general election.